Primary structure effects on peptide group hydrogen exchange
نویسندگان
چکیده
منابع مشابه
Primary structure effects on peptide group hydrogen exchange.
The rate of exchange of peptide group NH hydrogens with the hydrogens of aqueous solvent is sensitive to neighboring side chains. To evaluate the effects of protein side chains, all 20 naturally occurring amino acids were studied using dipeptide models. Both inductive and steric blocking effects are apparent. The additivity of nearest-neighbor blocking and inductive effects was tested in oligo-...
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ژورنال
عنوان ژورنال: Proteins: Structure, Function, and Genetics
سال: 1993
ISSN: 0887-3585,1097-0134
DOI: 10.1002/prot.340170110